Preventive Effects of Vitamin E and Catechin on Spermatogenic Disturbance Induced by Di-(2-Ethylhexyl) Phthalate in Rat
2007
Lee, J.W. (Cheju National University, Jeju, Republic of Korea) | Lee, K.K. (Cheju National University, Jeju, Republic of Korea) | Cheong, J.T. (Cheju National University, Jeju, Republic of Korea) | Yun, Y.M. (Cheju National University, Jeju, Republic of Korea) | Lee, J.M. (Cheju National University, Jeju, Republic of Korea) | Park, H.J. (Cheju National University, Jeju, Republic of Korea) | Woo, H.C. (Cheju National University, Jeju, Republic of Korea) | Yoo, J.G. (Gyeongsang National University, Jinju, Republic of Korea) | Son, W.J. (Gyeongsang National University, Jinju, Republic of Korea) | Kang, M.S. (Cheju National University, Jeju, Republic of Korea) | Kang, T.Y. (Cheju National University, Jeju, Republic of Korea), E-mail: [email protected]
The purpose of the present study was to determine the preventive effects of the two antioxidant vitamin E and catechin on DEHP-induced disturbance of spermatogenesis in male rats. Rats at 4 weeks of age were randomly allocated into five groups with 20 animals per group. The first group was not any administrated as control. The second group was administrated DEHP (2 g/kg) daily for 14 days. The third group was administrated vitamin E (500 IU/kg) following DEHP treatment by the same method (daily for 14 days).
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