Effects of ketamine hydrochloride on intraocular pressure and pupil diameter in dogs eyes | Ketamīna hidrohlorīda ietekme uz suņu acs iekšējo spiediena un zīlītes diametru
2008
Kovalcuka, L., Latvia Univ. of Agriculture, Jelgava (Latvia). Faculty of Veterinary Medicine | Birgele, E., Latvia Univ. of Agriculture, Jelgava (Latvia). Faculty of Veterinary Medicine
The objective of this study was to determine the effects of the ketamine hydrochloride on intraocular pressure (IOP) and horizontal pupil diameter (HPD) in dog's eyes. Dogs of different age, breed and sex were examined clinically and ophthalmologically. All animals were clinically and ophthalmologically healthy. Ten adult dogs were used for this study. All animals received 20 mg/kg ketamine intravenously. IOP and HPD were measured every 5 minutes for a total period of 35 minutes. It was established that due to the first five minutes after ketamine hydrochloride intravenous injection IOP increased significantly in booth eyes. A significant IOP increase was observed during all the research time - 35 minutes. Statistically significant pupil dilatation was observed only 5 minutes after the treatment. Because of ability to cause a significant IOP enlargement, ketamine alone should not be used in dogs with corneal trauma, laceration and ulceration or glaucoma.
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