Inhibition of lipid accumulation in 3T3-L1 adipocytes by extract of Chokong, Rhynchosia nolubilis seeds pickled in vinegar
2008
Shin, J.Y. (Korea Food Research Institute, Seongnam, Republic of Korea) | Park, L.Y. (Catholic University of Daegu, Gyungsan, Republic of Korea) | Oh, Y.S. (Catholic University of Daegu, Gyungsan, Republic of Korea) | Lee, S.H. (Catholic University of Daegu, Gyungsan, Republic of Korea) | Youn, K.S. (Catholic University of Daegu, Gyungsan, Republic of Korea) | Kim, S.J. (Dongduk Women's University, Seoul, Republic of Korea), E-mail: [email protected]
The anti-obesity effect of chokong, Rhynchosia nolubilis seeds Pickled in vinegars for 2 weeks at 4℃, was investigated. During the differentiation of 3T3-L1 adipocytes, the addition of ethanolic extracts of chokongs lowered the cellular triglyceride content by 8.1-9.0%, and glucose content by 12.2-27.6%, depending on the kinds of vinegar used. The activity of glycerol-3-phosphate dehydrogenase also decreased up to 56.0-59.3% by supplying those extracts. In addition, vinegars were superior to acetic acid, citric acid, and hydrochloric acid solutions, and distilled water in anti-obesity of the pickled seeds.
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