Food as ecosystem for transfer of resistant strains of microorganisms | Namirnice kao ekosistem za prenos resistentnih sojeva mikroorganizama
2009
Bulajic, S., Univerzitet u Beogradu, Beograd (Serbia). Fakultet veterinarske medicine | Mijacevic, Z., Univerzitet u Beogradu, Beograd (Serbia). Fakultet veterinarske medicine
The literature of the last few years provides evidence that antibiotic resistance traits have entered the microflora of farm animals and the food produced from them. Molecular analysis of the resistance genes, where available, shows that the food microflora is not separated from its human counterpart and conjuctive transfer of resistance genes has been demonstrated in vitro and in a few cases in vivo. For Salmonella typhimurium, resistance toward tetracyclines has increased from zero in 1948 to a 98% level in certain epidemic populations of S. typhimurium DT104. Although many of lactic acid bacteria (LAB) involved in food fermentation process has Generally Regarded as Safe (GRAS) status, risk potential based on possibility of resistance genes transfer from reservoir strains of LAB to human microflora has not been fully estimated. This situation reveals the antibiotic resistance problem of global dimensions highlightening the fact that the resistance problem will not be solved if there is a constant influx of resistance genes into the human microflora via food chain.
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