Antinociceptive and antipyretic activities of Amaranthus viridis Linn. in different experimental models
2010
Ashok Kumar, B.S., Sri K.V.College of Pharmacy, Chlickballapur, Karnataka (India) | Lakshman, K., PES College of Pharmacy, Bangalore, Karnataka (India) | Jayaveera, K.N., Jawaharlal Nehru Technological University of College of Engineering, Anantapur, Andhra Pradesh (India) | Sheshadri Shekar, D., Sri K.V.College of Pharmacy, Chlickballapur, Karnataka (India) | Vivek, C., Sri K.V.College of Pharmacy, Chlickballapur, Karnataka (India)
The methanolic extract of the whole plant extract of Amaranthus viridis L. (MEAV) was screened for antinociceptive activity using the acetic acid writhing test, hot plate test and tail immersion test in mice and for antipyretic activity using the yeast-induced pyrexia method in rats, at doses of 200 and 400 mg/kg body weight. Significant (p is less than 0.01) dose-dependent antinociceptive and antipyretic properties were observed with 200 and 400 mg/kg.
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