Porcine respiratory disease complex (PRDC) - a meta-analysis and sistematic review of the efficacy of enrofloxacin
2009
Golinar, I., Ljubljana Univ. (Slovenia). Veterinary Fac. | Valencak, Z. | Scuka, L., Krka d.d., Novo mesto (Slovenia)
Porcine respiratory disease complex (PRDC) is an economically significant disorder characterised by slow growth, decreased feed efficiency, lethargy, anorexia, fever, cough and dyspnea. A meta-analysis is a method of surveying and combining results of several independent clinical trials. Systematic reviews are concise summaries of the best available evidence that address sharply defined questions; they seek to assemble and examine all the high quality evidence on any given subject. This includes a comprehensive search of all potentially relevant articles and the use of explicit, reproducible criteria in the selection of articles for review. Enrofloxacin is a fluoroquinolone chemotherapeutic that was developed exclusively for use in veterinary medicine. The overall result of meta-analysis indicates a high efficacy of enrofloxacin (P 0.001) in treating PRDC. The mortality rate was lower in the groups which used enrofloxacin (P
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