Methoxyfenozide: effects on development, reproduction and some enzyme systems of the cotton leafworm, Spodoptera littoralis, boisd
2009
Mohamady, A.H. | Amin, T.R.
Methoxyfenozide (RH-2485) belongs to a new group of insect growth regulators (IGR's) with bisacylhdrazine structure that mimic the action of the natural insect moulting hormone. After ingestion of fourth larval instar to methoxyfenozide, percentage pupation and adult emergence were reduced as compared to control. No egg deposition was recorded when applied at 1.2 ppm (LC50 = 1.19 ppm). Percentage of eggs viability (methoxyfenozide hatchability) and sterility were 26.16 and 90.21, respectively, after treatment with 0.72 ppm. Accumulation of methoxyfenozide in the subsequent larval and pupal stages, might lead to significant macromolecular abnormalities. LC50 of methoxyfenozide reduced protein metabolism and detoxification enzymes. Biochemical readjustment after treatment was discussed. The effect of methoxyfenozide on detoxification enzymes, esterses and alkaline phosphatase, may be useful in the management of insect populations where insecticide resistance has developed as a result of elevated enzyme activities. It could be concluded that methoxyfenozide secondary and delayed effects on the cotton leafworm are significant and could be added to its acute toxic effects, so it is suggested that methoxyfenozide is potentially potent alternative for control of S. littoralis.
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