Folate compartments during gestational maturation.
Gross Samuel | Kamen Barton | Fanaroff Avroy | Caston Douglas
A recent study of 41 healthy preterm infants and 53 term infants revealed that almost 70% of the total folate is present in the bound form. Beyond the neonatal period, the fraction of bound folate drops to the level found in adults, which is approximately 30%. The increase in bound folate with increasing gestational maturity reflects fetal demand placed on folate transport and suggests an explanation for the loss of folate and the corresponding increase in unsaturated binder during pregnancy.
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