Mutagenicity of stable dust and drinking water on swine and cattle farms.
1995
Raszyk J. | Strnadova V. | Gajduskova V. | Ulrich R. | Jarosova A. | Pokorna Z. | Salava J. | Palac J.
Single pilot examinations of mutagenicity of stable dust and drinking water were made on three swine farms (D, M, T) and one cattle farm. The mutagenicity was examined by the Ames test using the indicator strains of Salmonella typhimurium with or without metabolic activation. At the same time the contents of selected pesticides and polychlorinated biphenyls (PCB) in stable dust and drinking water and that of polycyclic aromatic hydrocarbons (PAH) in stable dust were determined. Increased mutagenicity was demonstrated in drinking water and stable dust collected on the swine farm M. High content of PAH (8.246 mg/kg) and PCB (0.263 mg/kg) were also found in the dust samples collected on this farm. Only drinking water showed mutagenic activity on the swine farm D. On both the farms, the number of revertants was dose-dependent. Increased content of PAH (2.553 mg/kg) was also demonstrated in the dust samples collected on the farm D. No significant increase of mutagenic activity of stable dust or drinking water was demonstrable on the swine farm T and the cattle farm. Substances responsible for the mutagenicity of drinking water on the farms D and M have not yet been identified.
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