Formononetin influences growth and immune responses in broilers
2015
Iqbal, M.F. (University of Arid Agriculture, Rawalpindi (Pakistan). Faculty of Veterinary and Animal Sciences) | Khan, R.N.A. (University of Arid Agriculture, Rawalpindi (Pakistan). Faculty of Veterinary and Animal Sciences) | Hashim, M.M. (Gomal Univ., Dera Ismail Khan (Pakistan). Dept. of Food Science and Technology) | Ahmad, T. (University of Arid Agriculture, Rawalpindi (Pakistan). Faculty of Veterinary and Animal Sciences) | Mian, A.A. (University of Arid Agriculture, Rawalpindi (Pakistan). Faculty of Veterinary and Animal Sciences) | Ishaq, K. (University of Arid Agriculture, Rawalpindi (Pakistan). Faculty of Veterinary and Animal Sciences) | Rehman, A. (Poultry Research Inst., Rawalpindi (Pakistan))
Many in vitro studies indicate that flavonoids could exhibit a variety of potential beneficial effects as non-antibiotic feed additives. However, there is a dire need to ensure the in vivo contribution of flavonoids in animals. Present study was aimed at determining the growth promoting and immune modulating effects of formononetin in broilers. A total of 135 one day old Hubbard broiler chicks, randomly divided into 3 treatment groups, received a common basal diet with formononetin inclusion at 0 (control), 10 and 20 mg/kg of diet. The results indicated that 10 mg formononetin/kg of feed resulted in better FCR (P less than 0.05) from 21-42 and 0-42 days and significant increase in weight gain from 0-42 days of age. The dressing percentage was higher (P less than 0.05) in birds fed the diet supplemented with either 10 or 20 mg/kg of formononetin as compared to control group at 42 days of age. The dose of 10 mg/kg significantly enhanced the meat quality. Analysis of immunity related indices showed significant difference in the blood levels of PGF2, IL-10, IFN-gamma and LTB4 between the birds supplemented with either 10 or 20 mg forrnononetin/kg feed and control group depending upon the age of the birds. Overall, the results suggested that formononetin could positively affect the immune response and improve growth in broiler depending on their age and its dose.
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Эту запись предоставил National Agricultural Research Centre