Conservation of matrix protein genes in rabies viruses circulating in South Korea since 1999

Lee, Y.A., Food and Rural Affair, Gimcheon, Republic of Korea; Kim, H.H., Food and Rural Affair, Gimcheon, Republic of Korea; Yang, D.K., Food and Rural Affair, Gimcheon, Republic of Korea; Cho, I.S., Food and Rural Affair, Gimcheon, Republic of Korea

Conservation of matrix protein genes in rabies viruses circulating in South Korea since 1999

2017

Lee, Y.A., Food and Rural Affair, Gimcheon, Republic of Korea | Kim, H.H., Food and Rural Affair, Gimcheon, Republic of Korea | Yang, D.K., Food and Rural Affair, Gimcheon, Republic of Korea | Cho, I.S., Food and Rural Affair, Gimcheon, Republic of Korea

Rabies virus (RABV) causes a neurological disease in warm-blooded animals that is nearly always fatal. In this study, we analyzed the matrix (M) genes in 10 Korean street RABV strains isolated from two Provinces during 2011-2013. The M genes in these 10 Korean strains were highly conserved during 1999-2013. Phylogenetic analysis revealed they were closely related to the M genes of RABVs isolated in northeastern China. Specific amino acid substitutions were identified in the KRVB1206, KRVF1301, and BV9901PJ strains. However, functional domains, including those involved in virus production and pathogenicity, were conserved in all 10 strains.

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Ключевые слова АГРОВОК

filogenia genetic distance phylogenie phylogeny rabies virus

Библиографическая информация

Опубликовано в

Korean Journal of Veterinary Research

Том 57 Выпуск 4 ISSN 1225-0198

Нумерация страниц

pp. 249-252

Другие темы

Viral matrix proteins

Язык

Английский

Примечание

Summary(En)

1 table

2ill., 14 ref.

Тип

AGRIS — международная информационная система по сельскохозяйственным наукам и технологиям

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Conservation of matrix protein genes in rabies viruses circulating in South Korea since 1999

2017

Ключевые слова АГРОВОК

Библиографическая информация