New Orthopoxviruses spread among cattle in Georgia.
2020
Gulbani Ana
The recent discovery of a new Orthopoxvirus (OPXV): “Akhmeta Virus”, in Georgia (country) demonstrated the necessity for poxvirus detection and diagnosis capacity in this region. There is a dearth of data on OPXV circulation within the country. Human illness caused by this virus has implications for differential diagnosis of cutaneous lesion-producing zoonotic infections, particularly anthrax. Additionally, animal Orthopox virus infection may affect agricultural productivity and food safety. The main goal of the project was to enhance capacity for detection, diagnosis and report of human and animal OPXV infections and study disease prevalence in livestock. The study goal was successfully fulfilled with collaboration between the State Laboratory of Agriculture (SLA); the Centers for Disease Control and Prevention (CDC) Atlanta (US); National Food Agency (NFA) and the National Center for Disease Control and Public Health (NCDC) of Georgia. NFA veterinarians were trained to recognize cutaneous lesions among livestock and new assays were validated at SLA for detecting new OPXV variants in domestic animals found in Georgia. 3549 blood, milk, swab/scrubs samples were collected from different regions of the country; to date 1659 were tested on OPXV using Orthopoxvirus IgG ELISA and Orthopoxvirus Generic Real-Time PCR Assays.
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