CDKN2B-AS1 participates in high glucose-induced apoptosis and fibrosis via NOTCH2 through functioning as a miR-98-5p decoy in human podocytes and renal tubular cells
2021
Min Xiao | Shoujun Bai | Jing Chen | Yaxi Li | Shu Zhang | Zhao Hu
Highlights 1. CDKN2B-AS1 was upregulated in DN and high glucose-induced HPCs and HK-2 cells. 2. Inhibition of CDKN2B-AS1 alleviated high glucose-induced apoptosis and fibrosis of HPCs and HK-2 cells. 3. CDKN2B-AS1 regulated NOTCH2 expression via acting as a miR-98-5p sponge.
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