Immunization of Merino ewes with a synthetic inhibin peptide or with preparations obtained from bovine and porcine follicular fluids by immunoaffinity chromatography result in different effects on ovulation rate and on plasma gonadotrophin concentrations
1992
O'Shea, T. | Andrews, C.M. (New England Univ., Armidale (Australia). Dept. of Physiology) | Bindon, B.M. | Hillard, M.A. (Commonwealth Scientific and Industrial Research Organisation, Armidale (Australia). Div. of Animal Production) | Miyamoto, K. (Gumma Univ. School of Medicine (Japan)) | Sinosich, M.J. (Royal North Shore Hospital, St Leonards (Australia). Dept. of Obstetrics and Gynaecology)
Synthetic peptide with an amino acid sequence identical to that of the amino terminal of the alpha subunit of porcine inhibin, and bovine inhibin each increased ovulation rate and the number of follicles of the ewes; bovine inhibin, and not the peptide, increased plasma FSH and LH concentrations. Porcine inhibin had no effect on ovarian activity but markedly elevated plasma FSH and LH. The results suggest that ovulation rate is at least partly determined by intraovarian factors.
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