Antioxidant responses of Hericium erinaceus ingredients based on response surface methodology
2021
He, H. Q. | Liu, M. X. | Jiang, S. J.
Hericium erinaceus, a type of wood-rotting mushroom with many bioactive compounds, is effective to prevent and treat many human diseases. In order to acquire more bioactive materials, evaluation of extraction efficiencies, influencing factors, and available antioxidant activities of water and ethanol extractions were investigated by response surface methodology. The antioxidant activities (reducing power, scavenging activities of DPPH, superoxide anion radical, and hydroxyl radicals) and material contents (protein, polyphenol, and flavonoid) were optimised by a Box-Behnken design. The results showed that extraction temperature and solid-liquid ratio were the dominant factors influencing most responses. In addition, it was difficult to maximise all of the responses simultaneously under any set of condition groups. Flavonoid was the main contributor to the scavenging activity of DPPH and superoxide anion, while protein and polyphenol majorly affected the reducing power and scavenging activity of hydroxyl radicals. The antioxidant activities of the same fruiting bodies were related to extraction conditions, chemical constitutions, and physicochemical properties of the extractions. Following these results, further research on the extracts to identify important bioactive compounds for potential nutraceutical and medicinal use is underway.
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Эту запись предоставил Universiti Putra Malaysia