Flavonoides como agentes quimiopreventivos y terapéuticos contra el cáncer de pulmón
2012
Cabrera, Albert | Mach, Núria | Àrea de Ciències de la Salut, Institut Internacional de Postgrau ; Universitat Oberta de Catalunya [Barcelona] (UOC) | Génétique Animale et Biologie Intégrative (GABI) ; Institut National de la Recherche Agronomique (INRA)-AgroParisTech
The objective of the present review is to study the relationship between flavonoids and lung cancer, proposing that their regular consumption in Western diets could be beneficial for protecting patients against lung cancer.An extensive search of the scientific literature was performed in the following electronic specialized databases (PubMed central (PMC)-NBCI, Elsevier Journal, SciELO Spain, Scirus, Science Direct), including studies in animals, cells, and humans, in order to establish the effect of flavonoids in the prevention and development of lung cancer.Although in vitro and animal studies show the potential ability of flavonoids to act against different types of cancers, especially against lung cancers, the diverse results reported within epidemiological studies, together with the lack of experiments in humans, are the major factors in limiting making dietary recommendations based on scientific evidence for the management of patients with lung cancer. Therefore, the authors of the present study recommend following the dietary health practice guidelines which promotes the consumption of food enriched in flavonoids and reflects the current state of knowledge of an effective and appropriate diet in lung cancer patients.
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