Breeding animals for quality products: not only genetics
Chavatte-Palmer, Pascale | Couturier-Tarrade, Anne | Kiefer, Hélène | Duranthon, Véronique | Jammes, Hélène | Biologie du Développement et Reproduction (BDR) ; École nationale vétérinaire - Alfort (ENVA)-Institut National de la Recherche Agronomique (INRA) | International Embryo Transfer Society (IETS). USA.
The authors are members of European COST actions FA1201 EPICONCEPT (Epigenetics and Periconception Environnment) and BM1308 SALAAM (Sharing Advances on Large Animal Models)
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Показать больше [+] Меньше [-]Английский. The effect of the Developmental Origins of Health and Disease on the spread of non-communicable diseases is recognised by world agencies such as the United Nations and the World Health Organization. Early environmental effects on offspring phenotype also apply to domestic animals and their production traits. Herein, we show that maternal nutrition not only throughout pregnancy, but also in the periconception period can affect offspring phenotype through modifications of gametes, embryos and placental function. Because epigenetic mechanisms are key processes in mediating these effects, we propose that the study of epigenetic marks in gametes may provide additional information for domestic animal selection.
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