The pathogenesis of congenital radial head dislocation/subluxation
2016
Al-Qattan, Mohammad M. | Abou-Al-Shaar, Hussam | Alkattan, Wael M.
The pathogenesis of congenital radial head dislocation/subluxation is unknown and has not been previously investigated. In this review, we explore the pathogenesis and define five different primary insults: collagen abnormalities, abnormal endochondral ossification of the developing growth plate, abnormalities of forearm ossification outside the growth plate, disproportionate growth of the radius and ulna, and altered HOX D expression/activity. Finally, the clinical relevance of our review is discussed.
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