Characterization of New Ent-kaurane Diterpenoids of Yunnan Arabica Coffee Beans
2016
Chu, Rui | Wan, Luo-Sheng | Peng, Xing-Rong | Yu, Mu-Yuan | Zhang, Zhi-Run | Zhou, Lin | Li, Zhong-Rong | Qiu, Ming-Hua
Five new ent-kaurane diterpenoids, named mascaroside III–V (1–3), and 20-nor-cofaryloside I–II (4–5), together with seven known diterpenoids, were isolated from methanol extracts of the green coffee beans of Yunnan Arabica Coffee. Their chemical structures were elucidated by extensive spectroscopic analyses. Meanwhile, cytotoxicity assay against HL-60, A-549, SMMC-7721, MCF-7 and SW480 cell lines showed that they have not evident inhibition of cytotoxicity.
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