Influence of dietary protein level on growth: effect of clenbuterol
1991
Perez-Llamas, F. | Sastre, J.F. | Zamora, S.
The influence has been studied of a beta-agonist, clenbuterol, on body weight increase, feed efficiency and muscular tissue growth in Wistar rats of two different weights (70 and 200g) fed with a diet of differing protein levels (4, 10 and 15%). Treatment with clenbuterol had a negative influence on body growth and feed efficiency when the animals were fed with low protein diets (4%). With a higher protein content (10 and 15%), the situation changed completely, and these indices increased, with a relationship appearing between these changes, the agonist dose and the animal's age. In all the experiments clenbuterol improved muscle/body ratio significantly (P < 0.001). The favourable effect of clenbuterol on muscle growth is due to a specific increase in protein deposition and not to changes in the water content of muscular tissue, even though these changes may be produced.
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