The role of spacers on the self-assembly of DNA aptamer-amphiphiles into micelles and nanotapes
2013
Pearce, Timothy R. | Waybrant, Brett | Kokkoli, Efrosini
The self-assembly of single-stranded DNA (ssDNA) aptamer-amphiphiles was influenced by the choice of spacer used to link the hydrophobic tail and aptamer headgroup. Aptamer-amphiphiles without spacers or with hydrophilic spacers formed globular micelles while amphiphiles with hydrophobic spacers formed bilayer nanotapes, which are the first such structures formed by DNA-amphiphiles.
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