Measurement of estrogen receptors in normal and neoplastic lymph node tissue from dogs

Vicini, D.S.; Ogilvie, G.K.; Katzenellenbogen, J.; Carlson, K.

Measurement of estrogen receptors in normal and neoplastic lymph node tissue from dogs

1991

Vicini, D.S. | Ogilvie, G.K. | Katzenellenbogen, J. | Carlson, K.

Estrogen receptors were measured in normal canine lymph nodes and neoplastic tissue from dogs with lymphoma, using a commercially available [3H]estradiol dextran-coated charcoal assay. Using the same assay, estrogen receptors were detected in the positive-control tissues--dog uterus, rat uterus, and lyophilized bovine uterus. Specific binding of [3H]estradiol was not detected in rat skeletal muscle or in any of the canine lymphoid tissues, indicating that the specimens did not contain estrogen receptors.

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