Serum lipid and lipoprotein profiles in childhood
1983
Farinaro, E. | Giumetti, D. | Coraggio, S. | Panico, S. | Mancini, M.
Data on mean serum lipid and lipoprotein levels in male and female children and infants are reviewed briefly and discussed. Serum cholesterol at birth and during childhood predominantly is carried by low-density (LDL) and high-density (HDL) lipoprotein, while very-low-density lipoprotein (VLDL) remains very low during this period. Longitudinal studies show serum cholesterol decreasing slightly with age in boys (but not in girls), with the trend most evident between ages 10-14. LDL cholesterol follows this same trend. A slight, monotonous increase of total and VLDL serum triglycerides occurs with age, while HDL cholesterol appears to remain about constant. On the other hand, LDL cholesterol increases markedly between newborns and young children. The results in children confirm that high cholesterol levels may be present at early ages, suggesting that follow-up studies are needed to assess whether childhood hypercholesterolemia may correlate with future coronary disorders. (wz)
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