Insulin resistance in malnutrition-related diabetes mellitus is not mediated by insulin antibodies
1992
Rao, R.H.
Malnutrition-related diabetes mellitus (MRDM) comprises at least two different clinical patterns termed protein deficient (type J) diabetes and fibrocalculous pancreatic diabetes, which are both seen in young individuals and are distinguished by the pancreatic failure characteristically seen in the latter. The purpose of this study was specifically to determine whether circulating antibodies to insulin contribute to insulin resistance in MRDM, as a first attempt to identify the pathophysiological basis for the insulin resistance seen in MRDM.
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