A straightforward enantioselective synthesis of F17807
2015
Alliot, Julien | Gravel, Edmond | Buisson, David-Alexandre | Larquetoux, Laurent | Nicolas, Marc | Doris, Eric
An efficient approach for the enantioselective synthesis of the 1,4-benzodioxane F17807 drug is reported. The developed route relied on two key steps, namely SNAr and Mitsunobu reactions, which permitted a straightforward access to the title compound with full preservation of the enantiomeric excess throughout the synthetic sequence.
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