Neuroendocrine control of sex pheromone biosynthesis in Heliothis peltigera
1993
Altstein, M. | Gazit, Y. | Dunkelblum, E.
Sex pheromone production in female moths is controlled by a cerebral factor termed pheromone biosynthesis activating neuropeptide (PBAN). Our understanding of the sequence of events common to the neuroendocrine process of PBAN, namely, its biosynthesis, secretion, transport, biological activity, and degradation, is very limited. Moreover, some of the studies are controversial, mainly those related to: (1) the route of transport of PBAN to its target organ, (2) the nature of the target organ of PBAN, (3) the possible involvement of other stimulatory, and inhibitory neural and nonneural factors in the regulation of sex pheromone biosynthesis, (4) the structure-function relationship of the neuropeptide, and (5) the effect of PBAN on the enzymatic steps involved in pheromone biosynthesis in the gland. In this work, we summarize the results obtained in our laboratory on the regulation of sex pheromone biosynthesis by PBAN in Heliothis peltigera and shed light on some of these controversial issues.
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