Experimental Infection of Common Warthogs (Phacochoerus africanus) and Bushpigs (Potamochoerus larvatus) with Classical Swine Fever Virus. I: Susceptibility and Transmission
2011
Everett, H. | Crooke, H. | Gurrala, R. | Dwarka, R. | Kim, J. (Jinchoon) | Botha, B. | Lubisi, A. | Pardini, A. | Gers, S. | Vosloo, W. | Drew, T.
An incursion of classical swine fever virus (CSFV) into the domestic pig population in South Africa, identified in 2005, raised the concern that infection might spread to wildlife species and be maintained in these hosts. This study sought to determine whether two wildlife Suidae species present in South Africa, the bushpig (Potamochoerus larvatus) and the common warthog (Phacochoerus africanus), could support productive CSFV infection. Both species could be infected with CSFV and transmitted infection to in-contact animals of the same species. Viral antigen and RNA genome were detected in blood/serum and animals that survived initial infection seroconverted approximately 10-14 days post-inoculation. Viral RNA remained detectable in nasal and saliva secretions for prolonged periods until monitoring ended at 42-44 days after initial challenge. These data suggest that both Suidae species could serve to spread circulating CSFV within wild populations, with implications for disease control.
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