Synthesis of 2-substituted benzothiazoles via the Brønsted acid catalyzed cyclization of 2-amino thiophenols with nitriles
2019
Yu, Xiaoqiang | Yin, Qing | Zhang, Zhiheng | Huang, Tianyu | Pu, Zichao | Bao, Ming
A convenient and efficient method for the synthesis of 2-substituted benzothiazoles from simple and readily available 2-amino thiophenols and nitriles is described. The Brønsted acid-catalyzed cyclization reaction was performed under metal and solvent-free conditions.
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