Dietary vitamin A and risk of cancer in the Western Electric Study
1981
Shekelle, Richard B. | Liu, Shuguey | Raynor, William J. Jr | Lepper, Mark | Maliza, Carol | Rossof, Arthur H. | Paul, Oglesby | Shryock, Anne MacMillan | Stamler, Jeremiah
A prospective epidemiological study of 1954 men, aged 40-55, focused on the relationship of dietary intake of retinol (preformed vitamin A) and carotene (provitamin A) to incidence of lung cancer over 19 years. A 1-hour interview and a questionnaire were administered twice at a 1 year interval, to determine the subjects' food intake for the previous 28 days. It was found that intake of carotene was inversely related to incidence of lung cancer; intakes of retinol and other nutrients were not significantly related. Intakes of carotene and retinol were not significantly related to the incidence of other carcinomas as a group, or to the risks of developing other diseases that are related to smoking. (cj)
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