Polyoxygenated cyclohexene derivatives from Monanthotaxis congoensis

Starks, Courtney M.; Williams, Russell B.; Rice, Stephanie M.; Norman, Vanessa L.; Lawrence, Julie A.; Goering, Matt G.; O’Neil-Johnson, Mark; Hu, Jin-Feng; Eldridge, Gary R.

Polyoxygenated cyclohexene derivatives from Monanthotaxis congoensis

2012

A phytochemical investigation of Monanthotaxis congoensis afforded eight polyoxygenated cyclohexenes as well as the known crotepoxide. Structures were determined using NMR, MS, and optical rotation analyses. One compound displayed moderate antiproliferative activity against NCI-H460 and M14 cancer cells.

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Ключевые слова АГРОВОК

annonaceae antineoplastic agents chemistry drug therapy epoxy compounds humans neoplasms neoplasms nuclear magnetic resonance spectroscopy pharmacology plant extracts

Библиографическая информация

Опубликовано в

Phytochemistry

Том 74 Нумерация страниц 185 - 189 ISSN 0031-9422

Издатель

Elsevier Ltd

Другие темы

Drug effects; Phytogenic; Cyclohexenes; Cell line; Tumor; Cell proliferation; Monanthotaxis; Cyclohexenes; Therapeutic use; Molecular structure; Isolation purification

Язык

Английский

Лицензия

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Тип

Journal Article; Text

В АГРИСе с: 2024-02-28

Формат: MODS

Поставщик данных

Эту запись предоставил National Agricultural Library

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Ссылки

DOI http://dx.doi.org/10.1016/j.phytochem.2011.10.014

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