Analysis of the angiotensin-converting enzyme inhibitors perindopril, lisinopril, and quinapril by HPLC
2011
Khomushku, G. M | Zhloba, A. A | Puchnin, V. S | Arkhipova, M. V | Moiseeva, S. M
A unified HPLC method for analyzing the angiotensin-converting enzyme (ACE) inhibitors perindopril, lisinopril, and quinapril using a single column with a nonpolar phase based on octadecylsilica gel and a universal eluant (a mixture of acetonitrile and aqueous heptanesulfonic acid and triethylamine) is described; this method significantly decreases workload and the cost of analysis. The method can be used for the analysis of substances and different therapeutic formulations containing ACE inhibitors.
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