Comparative excretion of DDT analogues into milk of Indian buffalo, Bubalis bubalis L. following oral administration
1993
Kapoor, S.K. | Kalra, R.J.
Four groups of Indian buffaloes were fed daily with 25 mg of p,p'-DDT, p,p'-TDE, p,p'-DDE or o,p'-DDT for 100 days. Milk was analysed for organochlorine residues during this period and also for 100 days after pesticide administration had been discontinued. For the period showing plateau level' residues, 17.2% of p,p'-DDE, 17% of p,p'-TDE, 14% of p,p'-DDT as p,p'-DDT (3.5%); p,p'-TDE (10.5%), 3.2% of o,p'-DDT as o,p'-DDT (1.3%) and o,p'-TDE (1.9%) of their administered amounts were excreted in the milk. Since these compounds were excreted at different rates, the residue levels in the milk expected from a given feed would depend on their concentration and proportional distribution in the feed. The maximum tolerable content of DDT analogues in feed was derived to be 0.1 mg kg-1 (dry weight basis) by using the maximum accumulation coefficient and incorporation of the necessary safety margin. It is concluded that Indian buffaloes fed with rations contaminated with a total of DDT analogues below this limit will yield milk of acceptable quality. Following the termination of feeding with contaminated rations, the elimination of p,p'-DDE in the milk took the longest time and that of o,p'-DDT the shortest. These results suggest that the time required for the initial high residue concentration to decline to less than the legal lirnit would be determined by the relative amounts of DDE, TDE and DDT in the milk, after elimination of the potent source of contamination.
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