Data sought on low cholesterol and cancer
1981
A review on numerous past studies and present investigations seems to imply an association between low serum cholesterol and increased incidence of cancer. One study on the relationship of cholesterol to heart disease revealed the link to colon cancer; others have supported this observation. The Framingham study showed the cancer-cholesterol association for men only. Four studies have shown no correlation, but 2 other groups who found a link discovered that it disappeared with time. Possible explanations include a theory that low cholesterol is the result, not the cause of cancer; or, that a third factor is responsible, such as low vitamin A concentrations or increased sterols in the intestines associated with low cholesterol. The individual's serum cholesterol level may be the best presently available indication of the need for diet modification--cholesterol above 250 mg per 100 ml serum warrants a cholesterol-reducing diet, but benefits of reducing level below 200 mg seem questionable.
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