Isolation and identification of a slug-specific molluscicide from quackgrass (Agropyron repens, L. Beauv.)
1991
Hagin, R.D. | Bobnick, S.J.
A quackgrass (Agropyron repens, L. Beauv.) extract fraction containing "phenolic glycosides" showed both dermal and gastrointestinal toxicity toward the two slug species Deroceras reticulatum (Muller) and Deroceras laeve (Muller). These same phenolic glycosides were tested, with no apparent effect, against three freshwater snail species and a garden soil worm. The active compound in the phenolic glycoside fraction, 6-hydroxy-1,2,3,4-tetrahydro-beta-carboline-3-carboxylic acid (6-HTbetaC-3-COOH), was identified by use of TLC, CIMS, UV, and IR spectrophotometry, and comparison of the isolate to authentic compounds. The LD50 for the more resistant slug, D. laeve, tested against 6-HTbetaC-3-COOH, was estimated at approximately 5 mg/kg. A bait, containing 6-HTbetaC-COOH as the active ingredient, was highly active when field tested against the slug Arion subfuscus (Draparnaud). A survey of the literature indicated that 6-HTbetaC-COOH possesses little or no mammalian toxicity.
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