Low pressure supercritical CO2 extraction of astaxanthin from Haematococcus pluvialis demonstrated on a microfluidic chip
2018
Cheng, Xiang | Qi, ZhenBang | Burdyny, Thomas | Kong, Tian | Sinton, David
This study demonstrates the efficacy of low pressure supercritical CO₂ extraction of astaxanthin from disrupted Haematococcus pluvialis. A microfluidic reactor was employed that enabled excellent control and allowed direct monitoring of the whole process at the single cell level, in real time. Astaxanthin extraction using ScCO₂ achieved 92% recovery at 55 °C and 8 MPa applied over 15 h. With the addition of co-solvents, ethanol and olive oil, the extraction rates in both experiments were significantly improved reaching full recovery within a few minutes. Notably, for the ethanol case, the timescales of extraction process are reduced 1800-fold from 15 h to 30 s at 55 °C and 8 MPa, representing the fastest complete astaxanthin extraction at such low pressures.
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