Effects of live yeast (Saccharomyces cerevisiae) as a substitute to antibiotic on growth performance, immune function, serum biochemical parameters and intestinal morphology of broilers
He, Tengfei | Mahfuz, Shad | Piao, Xiangshu | Wu, Di | Wang, Wentao | Yan, Haibo | Ouyang, Tong | Liu, Yahui
This study evaluated the effects of live yeast (LY, Saccharomyces cerevisiae) on growth performance, nutrient digestibility, immune function, antioxidant status and intestinal morphology of broilers. A total of 224, 1 day-old broilers were assigned 4 treatments (7 replications, 8 chicks each) and fed a basal diet control group (CTR); antibiotic group (CTC) fed the basal diets with chlortetracycline at 75 mg/kg; LY-1 and LY-2 groups treated the basal diets with LY at 500 and 1000 mg/kg, respectively. Final body weight was greater (p < 0.05) in LY-2 group compared with the CTR. Crude protein retention was higher (p < 0.05) in both LY groups than that of the CTR. After immunization of birds with Newcastle diseases and Infectious bursal disease vaccine, the antibody titers were higher (p < 0.05) in LY-2 fed group than the CTR or CTC on day 35. Super oxide dismutase and catalase enzyme values were increased (p < 0.05) in LY groups than those of the CTR on day 42. Total cholesterol was lower (p < 0.05) in the LY-2 group than the CTR on day 42. Villus height in jejunum and ileum was higher (p < 0.05) in the LY-2 fed group than the CTR. Live yeast can be useful as a possible alternative to antibiotics in broilers.
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