Efficacy of an in-fed ivermectin formulation against gastrointestinal helminths, lungworms, and sarcoptic mites in swine

Alva-Valdes, R.; Wallace, D.H.; Foster, A.G.; Ericsson, G.F.; Wooden, I.W.

Efficacy of an in-fed ivermectin formulation against gastrointestinal helminths, lungworms, and sarcoptic mites in swine

1989

Alva-Valdes, R. | Wallace, D.H. | Foster, A.G. | Ericsson, G.F. | Wooden, I.W.

The efficacy of ivermectin as an in-feed formulation was evaluated against naturally acquired gastrointestinal helmiths, lungworms, and sarcoptic mites (experiment 1; n = 24) and against induced infection with intestinal nematodes (experiment 2; n = 24) in pigs. Treatments consisted of ivermectin administered in feed at concentrations calculated to provide 100 or 200 microgram/kg of body weight/d for 7 days or of nonmedicated feed (controls) for 7 days. At concentration of 100 microgram of ivermectin/kg/d, efficacy against naturally acquired infections was 97.7% for Ascaris suum, 97.8% for Metastrongylus spp, greater than 99% for Oesophagostomum spp, 100% for Macracanthorhynchus hirudinaceus, and 89.7% for Ascarops strongylina. Against induced infections (fourth-stage larvae), efficacy was 100% for A suum and 96.9% for Oesophagostomum spp. At concentration of 200 microgram of ivermectin/kg/d, efficacy against naturally acquired infections was 100% for A suum, Hyostrongylus rubidus, Metastrongylus spp; and 85.9% for Macracanthorhynchus hirudinaceus. Against induced infection (fourth-stage larvae), efficacy was 100% for A suum and 95% for Oesophagostomum spp. At concentrations of 100 and 200 microgram of ivermectin/kg/d, efficacy against Sarcoptes scabiei var suis was evidenced by elimination of the mite by posttreatment day 14.

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