Serum distribution of iodine after oral administration of ethylenediamine dihydriodide in cattle

Maas, J.; Berg, J.N.; Petersen, R.G.

Serum distribution of iodine after oral administration of ethylenediamine dihydriodide in cattle

1989

Maas, J. | Berg, J.N. | Petersen, R.G.

Serum concentrations of iodine were determined after cattle were given ethylenediamine dihydriodide (EDDI) orally at dosages ranging from 0.0 (placebo) to 0.77 mg/kg of body weight/day. The serum iodine concentration was correlated with the dosage of EDDI. A rate of 0.11 mg EDDI/kg/day was correlated with serum iodine concentrations (20 to 80 micrograms/dl) previously found to be effective in preventing foot rot in cattle. A linear dose-response curve that was generated could be helpful in predicting dosage of EDDI if the serum iodine concentration is known.

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