Comparison of a rice-based, mixed diet versus a lactose-free, soy-protein isolate formula for young children with acute diarrhea
1994
Maulen-Radovan, I. | Brown, K.H. | Acosta, M.A. | Fernandez-Varela, H.
A randomized clinical trial was completed to compare the efficacy of a mixed diet composed of locally available foods versus a lactose-tree, soy-based formula for the management of young Mexican children with acute diarrhea and dehydration. A total of 87 patients between 5 and 36 months of age received either a blended mixed diet containing rice, chicken, carrots, beans, and vegetable oil (group MD) or a soy formula (group SF) immediately after standard oral rehydration therapy. The initial clinical characteristics of the patients In each group were similar, as were their stool outputs during the first 6-hour period of rehydration before the diets were offered. There were six treatment failures, all of which were In group SF (p <0.01). The stool outputs of children In group MD and In group SF were 82 +/- 55 versus 112 +/- 88 gm/kg per day, respectively, on day 1 (p = 0.037), and 48 +/- 33 versus 66 +/- 55 gm/kg per day on day 2 (p = 0.109). The duration of diarrhea among those In group MD was significantly reduced compared with those in group SF (29 vs 67 hours; p <0.001). We conclude that the mixed diet resulted in improved clinical outcomes compared with the lactose-tree, soy protein isolate formula.
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