Room temperature dehalogenation of (hetero)aryl halides with magnesium/methanol
2018
Jouha, Jabrane | Khouili, Mostafa | Hiebel, Marie-Aude | Guillaumet, Gérald | Suzenet, Franck
Magnesium in methanol was found to be an effective and inexpensive reagent for the dehalogenation of (hetero)aryl chlorides, bromides and iodides under mild conditions. The halogen/hydrogen exchange proceeded at room temperature and tolerated functional groups such as esters, nitriles, alcohols, and alkenes.
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Эту запись предоставил National Agricultural Library