Cell biology of phlebovirus entry | Entrée cellulaire des phlébovirus chez l’hôte mammifère
2019
Uckeley, Zina M | Koch, Jana | Tischler, Nicole D | Léger, Psylvia | Lozach, Pierre-Yves | Heidelberg University Hospital [Heidelberg] | Department of Infectious Disease ; Hanoï Medical University | Molecular Virology Laboratory ; Fundación Ciencia & Vida ; Universidad San Sebastian = San Sebastian University [Santiago, Chile] (USS)-Universidad San Sebastian = San Sebastian University [Santiago, Chile] (USS) | Infections Virales et Pathologie Comparée - UMR 754 (IVPC) ; Institut National de la Recherche Agronomique (INRA)-École Pratique des Hautes Études (EPHE) ; Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Université Claude Bernard Lyon 1 (UCBL) ; Université de Lyon-Université de Lyon
National audience
Показать больше [+] Меньше [-]Английский. Phleboviruses constitute a large group of arthropod-borne viruses (arboviruses), mainly transmitted to their hosts by sandflies and ticks, occasionally by mosquitoes. These viruses have a worldwide distribution and many cause serious diseases - often fatal - in both domestic animals and humans. The global warming, the apparent wide distribution of arthropod reservoirs, and the increasing number of outbreaks show that phleboviruses must be taken seriously as emerging disease agents. This review proposes to focus on the early steps of phlebovirus infection, from virus binding to penetration into the cytosol. We address the most recent knowledge and advances in the entry of these viruses into vertebrate host cells, including virus receptors, cellular factors, endocytic pathways, and fusion.
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Библиографическая информация
Эту запись предоставил Institut national de la recherche agronomique