The effect of SCD and LEPR genetic polymorphisms on fat content and composition is maintained throughout fattening in Duroc pigs
Henriquez Rodriguez, Eliana | Bosch, L. | Tor i Naudí, Marc | Pena i Subirà, Ramona Natacha | Estany Illa, Joan
The effects of the stearoyl-CoA desaturase (SCD; AY487830:g.2228T > C) and leptin receptor (LEPR; NM_001024587:g.1987C > T) polymorphisms on fat content and fatty acid (FA) composition were investigated throughout fattening. Samples of Longissimus thoracis (LT) and subcutaneous fat (SF) from 214 Duroc barrows were collected from 160 days to slaughter age (220 days) using a longitudinal design. Results indicated that the positive effect of the T allele at the SCD gene on monounsaturated FA and of the T allele at the LEPR gene on saturated FA are maintained throughout the growing-finishing period, both in LT and SF. In LEPR, however, compositional changes, particularly in SF, are a result of increased fatness. There is very limited evidence of genotype by age interaction, and thus it is concluded that the combined selection for the SCD T and LEPR C alleles is a good strategy to increase the MUFA/SFA ratio regardless of the age at slaughter.
Показать больше [+] Меньше [-]This research was funded by the Spanish Ministry of Science and Innovation (MICINN, grant AGL2009-09779) and the Ministry of Economy and Competitiveness (MINECO, grant AGL2012-33529). EH-R is a recipient of a PhD scholarship from the University of Lleida.
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