A three-dimensional MRI atlas of the zebra finch brain in stereotaxic coordinates.
2008
Poirier, Colline | Vellema, Michiel | Verhoye, Marleen | Van Meir, Vincent | Wilderiane, Josiane | Balthazart, Jacques | Van Der Linden, Annemie
Английский. peer reviewed
Показать больше [+] Меньше [-]Английский. The neurobiology of birdsong, as a model for human speech, is a fast growing area of research in the neurosciences and involves electrophysiological, histological and more recently magnetic resonance imaging (MRI) approaches. Many of these studies require the identification and localization of different brain areas (nuclei) involved in the sensory and motor control of song. Until now, the only published atlases of songbird brains consisted in drawings based on histological slices of the canary and of the zebra finch brain. Taking advantage of high-magnetic field (7 Tesla) MRI technique, we present the first high-resolution (80 x 160 x 160 microm) 3-D digital atlas in stereotaxic coordinates of a male zebra finch brain, the most widely used species in the study of birdsong neurobiology. Image quality allowed us to discern most of the song control, auditory and visual nuclei. The atlas can be freely downloaded from our Web site and can be interactively explored with MRIcro. This zebra finch MRI atlas should become a very useful tool for neuroscientists working on birdsong, especially for co-registrating MRI data but also for determining accurately the optimal coordinates and angular approach for injections or electrophysiological recordings.
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Эту запись предоставил University of Liège