Coenzyme q10 in cardiovascular disease: an insight for a potential therapeutic benefit

Amit Zinabhai Chaudhari; Riyansi Satasia; Maulikkumar D. Vaja; Kishan Patel

Coenzyme q10 in cardiovascular disease: an insight for a potential therapeutic benefit

2023

Amit Zinabhai Chaudhari | Riyansi Satasia | Maulikkumar D. Vaja | Kishan Patel

The human body synthesizes the provitamin coenzyme Q10 (CoQ10), which plays a crucial role in the electron transport chain by ensuring a consistent and sufficient energy supply. CoQ10 exhibits multiple cellular roles, including its involvement in mitochondrial function, numerous cellular compartments, and plasma lipoproteins. Furthermore, CoQ10 plays a crucial role as an important antioxidant. The chemical composition of CoQ10 exhibits a strong correlation with vitamin K. It consists of a benzoquinone ring serving as the head group, accompanied by a tail made of ten isoprene units. A lack of CoQ10 has been identified as a fundamental factor contributing to numerous age-related and chronic illness problems. The efficacy of CoQ10 in various medical conditions has been proved by empirical evidence. Numerous research trials are now investigating the therapeutic and nutritional potential of CoQ10. CoQ10 continues to be predominantly utilized in the realm of cardiac research and reproductive treatments. However, there has been a notable surge of interest in exploring novel applications, notably in the context of topical administration.

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