Phycobiliproteins from cyanobacteria: Chemistry and biotechnological applications
Pagels, F | Guedes, A.C | Amaro, H.M | Kijjoa, A | Vasconcelos, V. | Centro Interdisciplinar de Investigação Marinha e Ambiental
Phycobiliproteinsareagroupofwatersolubleproteinswithanassociatedchromophore,responsibleforthelight-harvestingincyanobacteria.Theyaredividedinfourmaintypes:phycoerythrin,phycocyanin,phycoer-ythrocyanin and allophycocyanin, and they are characterized according to their structure and light qualityabsorption.Phycobiliproteinsfromcyanobacteriahavebeendescribedaspotentialbioactivecompounds,andrecognizedashigh-valuednaturalproductsforbiotechnologicalapplications.Moreover,phycobiliproteinshavebeenassociatedtoantioxidant,anticancerandanti-inflammatorycapacitiesamongothers.Thus,inordertoproducephycobiliproteinsfromcyanobacteriaforindustrialapplication,itisnecessarytooptimizethewholebioprocess,includingtheprocessingparameters(suchaslight,nitrogenandcarbonsource,pH,temperatureandsalinity)thataffectsthegrowthandphycobiliproteinaccumulation,aswellastheoptimizationofphycobili-proteinsextractionandpurification.Theaimofthisreviewistogiveanoverviewofphycobiliproteinsnotonlyin terms of their chemistry, but also in terms of their biotechnological applicability and the advances andchallengesintheproductionofsuchcompounds
Показать больше [+] Меньше [-]A PhD fellowship (reference SFRH/BD/136767/2018) for author F.P. was granted by Fundação para a Ciência e Tecnologia (FCT, Portugal). All the authors acknowledge the Interreg Atlantic Area pro- ject EnhanceMicroAlgae (EAPA_338/2016) funded by the European Regional Development Fund (ERDF), the project Algavalor (Regime Contratual de Investimento) cofunded by the ERDF and by the European Social Fund and the project ZEBRALGRE (PTDC/CVT-WEL/ 5207/2014), funded by national funds through FCT supported by COMPETE 2020: Programa Operacional Competitividade e Internacionalização (POCI)-01-0145-FEDER-016797.
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