EFFECTIVENESS OF DIAGNOSTIC USE OF CIFLUR® IN THE GOATS’ ENTOMOSIS

The economic losses of bovine animals from ectoparasites considerably exceed the costs caused by infectious diseases. Often, insects, mostly hemopoiesis, are the main provocative factor in outbreaks of bacteriosis and viruses in animal husbandry farms. For experiments, the modern repellant Ciflur® was selected, the active ingredient - the synthetic pyrethroid of the second type of ciflutrin. Investigations of insecticidal action of the drug were carried out in the summer of the year on goats, which were kept on the basis of the training farm ZNAEU. The presence of zootechnical flies Haematobia stimulans, Lyperosia irritans, Musca autumnalis, M. tempestiva, Tabanus bovinus, T. autumnalis and Oestrus ovis was regularly monitored indoors. The drug was applied to a dry, clean, intact skin of goats along the spine in the evening at a dose of 0,7 cm per 10 kg of body weight. After application, the water was not allowed to enter the place for 3 hours. The use of Ciflur® in goats was not accompanied by any local and systemic allergic and irritating effects. Absolute repellant action of the drug began to manifest itself from the third day after treatment of animals and lasted for 40 days. The use of Ciflur® did not affect the morphological parameters of goat's blood, indicating an indifferent response of the hemostasis system and bone marrow hematopoiesis of the goat's body to the use of insecticide. The minimal reaction of the organism to the administration of the drug appeared on the 15th day of the increased content of total protein (up to 78,86±0,60 g/l, p≤0,001) and creatinine (up to 116,5±1,29 mmol/l, p≤0,001) in serum, indicating some intense work of the liver and kidneys of experimental animals. The results obtained indicate the safety of Ciflur® for the female goat's body in the therapeutic dose applied and its high insecticidal and repellent efficacy against fly insects (zoophilous flies, gad-flies, and beast-flies) for 40 days.