SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication
2022
Yoichi Miyamoto | Yumi Itoh | Tatsuya Suzuki | Tomohisa Tanaka | Yusuke Sakai | Masaru Koido | Chiaki Hata | Cai-Xia Wang | Mayumi Otani | Kohji Moriishi | Taro Tachibana | Yoichiro Kamatani | Yoshihiro Yoneda | Toru Okamoto | Masahiro Oka
The SARS-CoV-2 ORF6, an antagonist of interferon-mediated antiviral signaling, directly binds to STAT1 and prevents its nuclear localization.
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