Cell-free synthesis of amyloid fibrils with infectious properties and amenable to sub-milligram magic-angle spinning NMR analysis
2022
Alons Lends | Asen Daskalov | Ansis Maleckis | Aline Delamare | Mélanie Berbon | Axelle Grélard | Estelle Morvan | Jayakrishna Shenoy | Antoine Dutour | James Tolchard | Abdelmajid Noubhani | Marie-France Giraud | Corinne Sanchez | Birgit Habenstein | Gilles Guichard | Guillaume Compain | Kristaps Jaudzems | Sven J. Saupe | Antoine Loquet
A method for cell-free synthesis of amyloid fibrils is reported that also allows for solid-state NMR analysis to characterize complex and pathological fibrillary assemblies.
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