The Simultaneous Administration of a Probiotic or Prebiotic with Live <i>Salmonella</i> Vaccine Improves Growth Performance and Reduces Fecal Shedding of the Bacterium in <i>Salmonella</i>-Challenged Broilers
Nahed A. El-Shall | Ashraf M. Awad | Mohamed E. Abd El-Hack | Mohammed A. E. Naiel | Sarah I. Othman | Ahmed A. Allam | Mahmoud E. Sedeik
Salmonellosis is one of the most important bacterial diseases in poultry, causing heavy economic losses, increased mortality and reduced production. The aim of this study was the comparative efficacy of a commercial probiotic and/or prebiotic with a live attenuated <i>Salmonella Enteritidis</i> (SE) vaccine on the protection of broiler chickens from SE challenge. The efficacy of probiotic or prebiotic products, as well as a live <i>Salmonella Enteritidis</i> (SE) vaccine at the 7th day of age, administered via drinking water, were evaluated for clinical protection and effects on growth performance of broiler chickens experimentally challenged with SE at the 28th day of age. The use of probiotic or prebiotic simultaneously with the live <i>Salmonella</i> vaccine can diminish the negative effect of live vaccine growth performance, reducing mortality rate, fecal shedding, and re-isolation of SE from liver, spleen, heart and cecum. The use of probiotic or prebiotic simultaneously with the application of the live <i>Salmonella</i> vaccine is a good practice to diminish the negative effect of the harmful bacteria and improve the growth performance of broilers. Thus, further studies may be carried out with layers and breeders.
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