Increased p63 expression in canine perianal gland tumours

Kim Soo-Hyeon; Seung Byung-Joon; Cho Seung-Hee; Lim Ha-Young; Park Hee-Myung; Sur Jung-Hyang

Increased p63 expression in canine perianal gland tumours

2018

p63 is a homologous molecule of p53 and was recently identified as playing important roles in several key cellular processes, including epithelial development and proliferation. Since then, several studies have demonstrated altered p63 expression in various cancers of epithelial origin. Canine perianal gland tumour is one of the most common skin neoplasms in dogs; however, the molecular characteristics of this tumour remain poorly understood. The objective of the present study was to analyse and compare the expression of p63 in canine perianal gland adenomas and carcinomas.

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